Chlorpromazine Warnings and Precautions

There is a lot of important information to be aware of before starting treatment with chlorpromazine. Warnings and precautions with this medicine include watching for symptoms of neuroleptic malignant syndrome, letting your healthcare provider know if you have liver or kidney disease, and looking out for certain drug interactions. You should not take chlorpromazine if you are allergic to any components of the medicine or are taking large doses of medications or substances that cause significant drowsiness.

 

Chlorpromazine: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking chlorpromazine hydrochloride (Thorazine®) if you have:
 
  • Kidney problems, such as kidney failure (renal failure)
  • Liver problems, including liver failure or cirrhosis
  • Breathing problems, including infections, asthma, or emphysema
  • Glaucoma
  • An enlarged prostate (also known as benign prostatic hyperplasia or BPH)
  • Difficulty passing urine
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also let your healthcare provider know if you:
 
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Have an upcoming surgery
  • Drink alcohol.
     
You should also be sure to tell your healthcare provider about all other medicines you may be taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Chlorpromazine Warnings and Precautions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;