Invega Sustenna Dosage

Invega Sustenna is a type of injection administered by a healthcare provider to treat schizophrenia. Your individual dosage of Invega Sustenna will depend on other medications you are taking, other medical conditions you may have, and various other factors. When first starting this medicine, the initial dosage is followed by a second one a week later. After that, the injections are given once a month.

An Introduction to Dosing With Invega Sustenna

The dose of Invega® Sustenna® (paliperidone palmitate) your healthcare provider recommends will vary, depending on a number of factors, including:
  • How you respond to the medication
  • Other medical conditions you may have
  • Other medications you are taking.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.

Recommended Invega Sustenna Dosage

The standard initial dosage of Invega Sustenna for the treatment of schizophrenia is a first-time dosage of 234 mg. A dose of 156 mg is given one week later, followed by a once-a-month maintenance dose of 117 mg given every four weeks.
Some people may be switched from paliperidone tablets (available as Invega®) to Invega Sustenna. The recommended maintenance dose to replace paliperidone tablets is as follows:
  • Invega Sustenna 234 mg every four weeks for people taking paliperidone 12 mg a day
  • Invega Sustenna 117 mg every four weeks for people taking paliperidone 6 mg a day
  • Invega Sustenna 39 to 78 mg every four weeks for people taking paliperidone 3 mg a day.
Some people may need lower or higher dosages, depending on how well the medication is tolerated and how well it works to control symptoms. The manufacturer recommends that maintenance doses be no lower than 39 mg and no higher than 234 mg.
People who are switching from another long-acting injectable antipsychotic to Invega Sustenna do not need to receive the first two doses that are given one week apart. Instead, they can begin their maintenance dosage on the day of their regularly scheduled antipsychotic injection.
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Invega Sustenna Medication Information

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