Loxapine Inhalation Powder
You should talk with your healthcare provider prior to using this medication if you have:
- Airway or lung problems, such as asthma or chronic obstructive pulmonary disease (COPD)
- Breathing problems, such as coughing, chest tightness, wheezing, or shortness of breath
- Low blood pressure (hypotension)
- High blood pressure (hypertension)
- Heart problems, including heart disease, heart failure, or heart rhythm problems
- Had a stroke or heart attack
- Ever had a seizure
- Liver disease, such as hepatitis, cirrhosis, or liver failure
- Used loxapine inhalation powder before and had trouble breathing
- Difficulty urinating
- Parkinson's disease
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you:
- Are pregnant or thinking of becoming pregnant (see Adasuve and Pregnancy)
- Are breastfeeding (see Adasuve and Breastfeeding)
- Regularly drink alcohol or use street drugs.
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Loxapine Inhalation Powder to learn more, including information on who should not use the drug.)
In clinical studies, loxapine inhalation powder was shown to quickly reduce agitation in people with schizophrenia or bipolar I disorder. In these studies, people with these disorders who were experiencing agitation were given either loxapine inhalation powder or a placebo inhaler (an inhaler with no active ingredient). After two hours, those given loxapine inhalation powder were significantly less agitated than those given the placebo. The effects of loxapine inhalation powder were apparent as soon as 10 minutes after the dose was given.