Loxitane and Pregnancy
In animal studies on Loxitane and pregnancy, the drug was shown to increase the risk of kidney problems in the fetus. As a result, the FDA considers it a pregnancy Category C medication. However, it may still be prescribed if the benefits to the woman outweigh the risks to the unborn child, so talk to your healthcare provider if you are taking Loxitane and pregnancy occurs.
Is Loxitane Safe During Pregnancy?Loxitane® (loxapine) may not be safe for women who are pregnant. In animal studies, the drug increased the risk of kidney problems in the fetus.
Loxitane and Pregnancy Category CThe U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but that do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
In animal studies, giving Loxitane to pregnant rats increased the risk of certain kidney problems in the newborn.
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if the healthcare provider believes that the benefits to the mother outweigh any possible risks to the unborn child.
If you are taking Loxitane and pregnancy occurs (or if you are thinking of becoming pregnant while taking the drug), let your healthcare provider know. He or she will consider both the benefits and risks of taking the medication during pregnancy before making a recommendation in your particular situation.