Loxitane Warnings and Precautions

Before starting a new drug, it is important to be aware of its warnings and precautions. For example, with Loxitane, warnings and precautions include understanding that the drug can increase your risk of liver damage, eye damage, and seizures, among other things. Also, the medication is not suitable for everyone. Loxitane warnings and precautions also extend to people who are allergic to Loxitane or are in a decreased state of consciousness.

Loxitane: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Loxitane® (loxapine) if you have:
 
Also, let your healthcare provider know if you:
 
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Drink alcohol.
     
You should also be sure to tell your healthcare provider about all of the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 

Specific Loxitane Warnings and Precautions

Warnings and precautions to be aware of prior to taking Loxitane include the following:
 
  • The medication can cause tardive dyskinesia. This is a condition involving unusual uncontrollable body or facial movements. The condition can become permanent even if Loxitane is stopped. The best way to prevent this is to tell your healthcare provider right away if you notice any abnormal movements (including abnormal movements of the tongue) while taking Loxitane.
     
  • Loxitane can cause a life-threatening condition called neuroleptic malignant syndrome (NMS). Some symptoms of NMS include:
o A high fever
o Stiff muscles
o Confusion
o Irregular pulse or blood pressure
o A fast heart rate (tachycardia)
o Sweating
o Irregular heart rhythms (arrhythmias).
Tell your healthcare provider right away if you think you might have NMS.
  • Loxitane can impair your mental or physical abilities to drive a car or operate heavy machinery. Make sure you know how the drug affects you before you do any activities that require mental concentration or physical coordination.
     
  • Loxitane can increase the risk of liver damage or eye damage. Be sure to let your healthcare provider know if you have signs of liver damage (such as yellow eyes or skin) or any vision changes while taking the drug.
     
  • Loxitane can increase the level of prolactin (a natural hormone) in your blood. This can cause various problems, such as breast enlargement, breast discharge, menstrual changes, or sexual problems.
     
  • Loxitane can cause a drop in blood pressure (hypotension). This can cause a person to have lightheadedness or dizziness or to faint. Tell your healthcare provider if you have any of these symptoms when standing. Hypotension can be especially dangerous in people with heart disease or congestive heart failure (CHF). Combining alcohol with Loxitane can also increase the risk of hypotension (see Alcohol and Loxitane).
     
  • The medication may increase the risk of seizures. Before starting Loxitane, tell your healthcare provider if you have epilepsy or a history of seizures.
     
  • Loxitane is considered a pregnancy Category C medication. This means that it may not be safe to take during pregnancy. Be sure to talk with your healthcare provider about the risks and benefits of using the drug while pregnant (see Loxitane and Pregnancy).
     
  • It is not known if Loxitane passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider before starting treatment (see Loxitane and Breastfeeding).
     
  • Loxitane can interact with certain other medications (see Loxitane Drug Interactions).
 
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