Schizophrenia Home > Abilify Maintena Drug Interactions
When antidepressants, blood pressure medications, or certain other drugs are taken with Abilify Maintena, negative interactions may occur. Among other things, these reactions can increase your risk for side effects or decrease the effectiveness of the medications. To help minimize your risk of problems, talk to your healthcare provider about all medications, vitamins, and supplements you are taking before starting treatment.
Abilify Maintena™ (aripiprazole ER injection) may react with a number of other products. Some of the drugs that can interact with Abilify Maintena include but are not limited to:
- CYP 2D6 inhibitor medications, such as:
- Bupropion (Aplenzin™, Budeprion SR®, Budeprion XL®, Buproban®, Wellbutrin®, Wellbutrin SR®, Wellbutrin XL®, Zyban®)
- Chlorpromazine
- Cinacalcet (Sensipar®)
- Cocaine
- Delavirdine (Rescriptor®)
- Fluoxetine (Prozac®, Sarafem®, Selfemra™)
- Lopinavir and ritonavir (Kaletra®)
- Paroxetine (Paxil®, Paxil CR®, Pexeva®, Brisdelle™)
- Quinidine
- Ritonavir (Norvir®)
- Terbinafine (Lamisil®)
- CYP 3A4 inducer medications, such as:
- Aminoglutethimide (Cytadren®)
- Bosentan (Tracleer®)
- Carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®)
- Dexamethasone (Decadron®, Dexpak®, Maxidex®)
- Efavirenz (Sustiva®)
- Efavirenz, emtricitabine, and tenofovir (Atripla®)
- Etravirine (Intelence™)
- Fosphenytoin (Cerebyx®)
- Nafcillin
- Nevirapine (Viramune®)
- Oxcarbazepine (Trileptal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Phenytoin (Dilantin®, Phenytek®)
- Primidone (Mysoline®)
- Rifabutin (Mycobutin®)
- Rifampin (Rifadin®)
- Rifapentine (Priftin®)
- St. John's wort
- CYP 3A4 inhibitor medications, such as:
- Amprenavir (Agenerase®)
- Aprepitant (Emend®)
- Atazanavir (Reyataz®)
- Clarithromycin (Biaxin®)
- Conivaptan (Vaprisol®)
- Darunavir (Prezista®)
- Delavirdine (Rescriptor®)
- Deferasirox (Exjade®)
- Diltiazem (Cardizem®, Cardizem CD®, Cardizem LA®, Cartia XT®, Dilacor XR®, Dilt-CD®, Diltia XT®, Dilt-XR®, Taztia XT®, Tiazac®)
- Erythromycin
- Fosamprenavir (Lexiva®)
- Imatinib (Gleevec®)
- Indinavir (Crixivan®)
- Isoniazid
- Itraconazole (Sporanox®)
- Ketoconazole (Nizoral®)
- Lopinavir and ritonavir (Kaletra®)
- Miconazole
- Nefazodone (Serzone®)
- Nelfinavir (Viracept®)
- Nicardipine (Cardene®)
- Posaconazole (Noxafil®)
- Quinidine
- Ritonavir (Norvir®)
- Saquinavir (Fortovase®, Invirase®)
- Telithromycin (Ketek®)
- Verapamil (Calan®, Calan SR®, Covera-HS®, Isoptin SR®, Verelan®, Verelan PM®)
- Voriconazole (Vfend®)
- Medications that cause drowsiness, such as:
- Alcohol
- Other antipsychotic medications
- Anxiety medications
- Most antidepressants
- Muscle relaxants
- Narcotic pain relievers
- Sleep medications
- Some antihistamines.