Schizophrenia Home > Seroquel XR

A healthcare provider may prescribe Seroquel XR to treat schizophrenia or bipolar disorder. This long-acting, extended-release medication works by blocking or lessening the effects of certain chemicals in the brain. It comes in the form of a tablet that is taken just once a day, typically in the evening. Although most people tolerate the drug well, side effects can still occur, such as drowsiness, dry mouth, and dizziness.

What Is Seroquel XR?

Seroquel XR® (quetiapine XR) is a prescription medication that is used to treat schizophrenia and bipolar disorder. When combined with an antidepressant, it is also approved for treating depression. It is a long-acting, extended-release medication that is taken just once a day.
(Click Seroquel XR Uses for more information, including possible off-label uses.)

Who Makes It?

Seroquel XR is manufactured by AstraZeneca Pharmaceuticals.

How Does This Medicine Work?

Seroquel XR is not a cure for schizophrenia or bipolar disorder. It only helps to control symptoms (see Symptoms of Schizophrenia or Bipolar Disorder Symptoms).
Seroquel XR belongs to a group of medications called second-generation (or atypical) antipsychotic medications. It is not entirely clear how this drug works to treat schizophrenia. However, it is known to block or lessen the effects of several chemicals in the brain. These chemicals (such as dopamine and serotonin) may be elevated in people with schizophrenia or bipolar disorder.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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