Schizophrenia Home > Trilafon and Pregnancy

Little is known about the specific effects of Trilafon on pregnancy. In animal studies that looked at phenothiazines, the medication did cross the placenta and reach the fetus. As a result, the FDA has classified Trilafon as a pregnancy Category C medication. If you are taking Trilafon and pregnancy occurs, your healthcare provider may still recommend its use if the benefits to you outweigh the risks to the fetus.

Is Trilafon Safe During Pregnancy?

Trilafon® (perphenazine) may not be safe for women who are pregnant. This is based largely on studies of other, similar medications, as little is known about the use of Trilafon during pregnancy.

Trilafon and Pregnancy Category C

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but that do appear to cause harm to the fetus in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Very little research has been done to see if Trilafon is safe for use during pregnancy (in either animals or humans). It is known that phenothiazines such as Trilafon cross the placenta and reach the fetus.
However, a pregnancy Category C medicine may be given to a pregnant woman if her healthcare provider believes that the benefits to the mother outweigh any possible risks to the unborn child.

Trilafon and Pregnancy: Final Thoughts

If you are taking Trilafon and pregnancy occurs (or if you are thinking of becoming pregnant while taking the drug), let your healthcare provider know. He or she will consider both the benefits and risks of using Trilafon during pregnancy before making a recommendation in your particular situation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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