Schizophrenia Home > Trilafon Warnings and Precautions

Specific Trilafon Warnings and Precautions

Warnings and precautions to be aware of prior to taking Trilafon include the following:
  • Trilafon can cause a life-threatening condition called neuroleptic malignant syndrome (NMS). Some symptoms of NMS include:
o A high fever
o Stiff muscles
o Confusion
o An irregular pulse or blood pressure
o A fast heart rate (tachycardia)
o Sweating
o Irregular heart rhythms (arrhythmias). 
Tell your healthcare provider right away if think you might have NMS.
  • The medication can cause tardive dyskinesia, a condition involving unusual and uncontrollable body or facial movements. The condition can become permanent even if Trilafon is stopped. The best way to prevent it from becoming permanent is to tell your healthcare provider right away if you notice any abnormal movements (including abnormal movements of the tongue) while taking Trilafon.
  • Trilafon can impair your mental or physical abilities to drive a car or operate heavy machinery. Make sure you know how the drug affects you before you do any activities that require mental concentration or physical coordination. Combining Trilafon with medications or substances that cause drowsiness (such as narcotics, alcohol, or barbiturates) can be dangerous (see Alcohol and Trilafon).
  • Trilafon can increase the level of prolactin (a naturally occurring hormone) in the body. This can cause side effects such as breast changes or breast discharge, menstrual changes, or sexual problems.
  • Since the kidneys help remove Trilafon from the body, be sure to tell your healthcare provider if you have kidney disease. You may need to be monitored more closely or may need a lower Trilafon dosage if this is the case.
  • Let your healthcare provider know if you have breathing problems, as Trilafon can make these problems worse.
  • The medication can increase your sensitivity to the sun, increasing your risk of sunburn. You should use sunscreen before sun exposure while taking Trilafon.
  • Trilafon can cause liver damage or eye problems when used for a long period of time.
  • Trilafon is considered a pregnancy Category C medication. This means that it may not be safe to take during pregnancy. Be sure to talk with your healthcare provider about the risks and benefits of using the drug while pregnant (see Trilafon and Pregnancy).
  • Trilafon passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Trilafon and Breastfeeding).
  • Trilafon can interact with certain other medications (see Trilafon Drug Interactions).
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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