It is not entirely known how Zyprexa works for schizophrenia or bipolar disorder. However, it is known that it blocks or lessens the effects of several chemicals in the brain. These brain chemicals (such as dopamine and serotonin) may be elevated in people with schizophrenia or bipolar disorder.
In previous clinical studies of this drug for the treatment of schizophrenia, people taking it experienced improvements in their schizophrenia symptoms (including hallucinations and suspiciousness), compared to those not taking it. Longer studies also showed that Zyprexa can help people from needing to be hospitalized and can help symptoms from returning.
Previous clinical studies have also shown the drug to be effective for bipolar disorder treatment. In these studies, the medication was effective when used alone or with other bipolar disorder medications.
(Click Zyprexa for more information about Zyprexa's uses, to learn about the potential side effects associated with this medicine, and for suggestions on when and how to take this drug.)
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Zyprexa Relprevv [package insert]. Indianapolis, IN: Eli Lilly and Company;2009 December.
Zyprexa [package insert]. Indianapolis, IN: Lilly USA, LLC;2013 July.
Food and Drug Administration, Center for Drug Evaluation and Research. Electronic orange book: Approved drug products with therapeutic equivalence evaluations. FDA Web site. Available at: http://www.fda.gov/cder/ob/. Accessed April 16, 2007.
Briggs GG, Freeman RK, Yaffe SJ. Drugs in Pregnancy and Lactation. 7th ed. Philadelphia (PA): Lippincott Williams & Wilkins; 2005.
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