Prochlorperazine Dosing (Cont.)

Prochlorperazine Dosing in Children

Prochlorperazine should not be used in children younger than two years of age or weighing less than 20 pounds. Also, it should not be used for nausea and vomiting in pediatric surgery. At one point, prochlorperazine suppositories in small dosages (for children) were available. However, only adult suppositories are currently available. Refer to the following table for the recommended prochlorperazine dose (for tablets or suppositories) for severe nausea and vomiting in children:
 
Weight
Usual Prochlorperazine Dose
Maximum Prochlorperazine Dose
20 pounds to 29 pounds
2.5 mg once or twice daily
7.5 mg per day
30 pounds to 39 pounds
2.5 mg two or three times daily
10 mg per day
40 pounds to 85 pounds
2.5 mg three times daily or 5 mg twice daily
15 mg per day
 
For schizophrenia treatment in children ages 2 to 12, the recommended starting dose is 2.5 mg two or three times daily.
 
(Prochlorperazine Dosing Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;