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Side Effects of Quetiapine
Dry mouth, drowsiness, high cholesterol, and agitation are a few common quetiapine side effects. However, most people tolerate the drug without problems. If side effects do occur, they are typically minor and easily treated. Some side effects with quetiapine, however, should be reported to a healthcare provider right away, such as abnormal muscle movements, signs of an allergic reaction, and an increased heart rate.
As with any medicine, side effects are possible with quetiapine fumarate (Seroquel®). However, not everyone who takes the drug will experience side effects. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with quetiapine. Your healthcare provider can discuss a more complete list of quetiapine side effects with you.)
Some side effects with quetiapine are potentially serious and should be reported immediately to your healthcare provider. These include, but are not limited to:
- Signs of diabetes, such as high blood sugar, increased thirst, frequent urination, or extreme hunger (see Seroquel and Diabetes)
- Large or rapid weight gain
- Suicidal thoughts
- Dizziness or fainting when going from a sitting or lying-down position to standing
- Feelings of internal restless or jitteriness
- Any abnormal muscle movements (these abnormal movements can become permanent if quetiapine is not stopped quickly)
- Signs or symptoms of neuroleptic malignant syndrome, which can include:
- A high fever
- Stiff muscles
- Confusion
- Irregular pulse or blood pressure
- An increased heart rate (tachycardia)
- Sweating
- Irregular heart rhythms (arrhythmias)
- Signs of an allergic reaction, including:
- Unexplained rash
- Hives
- Itching
- Unexplained swelling
- Wheezing
- Difficulty breathing or swallowing.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD