Stelazine is a prescription medicine that is licensed for the treatment of schizophrenia and anxiety. It is believed to work by blocking or lessening the effects of dopamine in the brain, which can become elevated in people with these conditions. The medication comes in tablet form, and is taken one to three times a day. Side effects of Stelazine can include drowsiness, dizziness, and blurred vision.

What Is Stelazine?

Stelazine® (trifluoperazine hydrochloride) is a prescription medicine that has been licensed to treat the following conditions:
(Click Stelazine Uses for more information, including possible off-label uses.)

Who Makes Stelazine?

Stelazine was originally manufactured by GlaxoSmithKline. Although brand-name Stelazine is no longer manufactured, a generic version is still available. It is made by several different companies.

How Does It Work?

Stelazine belongs to a group of medications called phenothiazines. When used to treat schizophrenia, it is known as a typical (or first-generation) antipsychotic medication. It is not entirely known how Stelazine works. However, it is known that the drug blocks or lessens the effects of dopamine, a chemical in the brain. Dopamine may be elevated in people with schizophrenia or anxiety. This medication is not a cure for schizophrenia or anxiety, however. It only helps to control symptoms (see Symptoms of Schizophrenia or Anxiety Symptoms).

When and How to Take Stelazine

The following are some general considerations for when and how to take this medication:
  • Stelazine comes in tablet form. It is taken by mouth two to three times a day.
  • You can take it with or without food. If the medication bothers your stomach, try taking it with food.
  • The medication should be taken at the same times each day to maintain an even level in your blood.
  • For the medicine to work properly, it must be taken as prescribed. It will not work if you stop taking it.
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Stelazine Drug Information

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