Zyprexa Dosage for Bipolar Depression or Treatment-Resistant Depression
When combined with
fluoxetine (
Prozac®),
Zyprexa is approved to treat
depression associated with
bipolar disorder or treatment-resistant depression (depression that has not responded to at least two different
antidepressants). The starting dosage is fluoxetine 20 mg daily, in combination with Zyprexa 5 mg daily. Your healthcare provider may adjust the amount of each medication as necessary.
General Information on Dosing With Zyprexa
Some considerations to keep in mind when taking Zyprexa include the following:
- Zyprexa is available in several forms, including regular tablets and tablets that are meant to dissolve rapidly in the mouth. These are called Zyprexa Zydis® tablets.
- Regular Zyprexa tablets should be taken with a glass of water. Zyprexa Zydis tablets do not need to be taken with water.
- Your dosage can be taken with or without food.
- This medication can be taken either in the morning or at night. However, Zyprexa should be taken at the same time each day to maintain an even level in your blood.
- If Zyprexa causes bothersome drowsiness or dizziness for you, ask your healthcare provider if you can take your dose at bedtime to decrease these side effects.
- For the medicine to work properly, it must be taken as prescribed. Zyprexa will not work if you stop taking it.
- If you are unsure about anything related to your dosage or Zyprexa dosing in general, talk with your doctor, nurse, or pharmacist. Do not stop taking this drug without first discussing it with your healthcare provider (see Withdrawal From Zyprexa).