Zyprexa Dosage

The recommended starting Zyprexa dose for schizophrenia is Zyprexa 5 mg to 10 mg once daily. For the treatment of bipolar disorder, the recommended starting dose is 10 mg to 15 mg once daily. With either condition, the maximum Zyprexa dosage is 20 mg a day. Your age and other medical conditions you may have are among the factors that can affect Zyprexa dosing.

 

An Introduction to Zyprexa Dosage

The dose of Zyprexa® (olanzapine) your healthcare provider recommends will vary depending on a number of factors, including:
 
  • The medical condition being treated
  • Your age
  • The severity of your condition
  • Other medical conditions you may have
  • Other medications you may be currently taking.
     
As always, do not adjust your Zyprexa dose unless your healthcare provider specifically instructs you to do so.
 

Zyprexa Dosing for Schizophrenia

The recommended starting Zyprexa dose for schizophrenia is Zyprexa 5 mg to 10 mg once daily. If you start at less than Zyprexa 10 mg daily, your healthcare provider may increase the dose of Zyprexa to 10 mg within the first few days.
 
After that, your healthcare provider may choose to increase the Zyprexa dosage further if symptoms continue or decrease the dose if side effects occur. The maximum dose for Zyprexa is 20 mg per day.
 

Zyprexa Dosing for Bipolar Disorder

The recommended starting Zyprexa dose for bipolar disorder is Zyprexa 10 mg to 15 mg once daily. If bipolar disorder symptoms continue after several weeks, your healthcare provider may increase the Zyprexa dosage.
 
If Zyprexa is used in combination with lithium (Eskalith®, Lithobid®) or valproate products (Depakene®, Depakote®, Depakote ER®), the recommended starting dose is generally Zyprexa 10 mg once daily.
 
Once your bipolar symptoms are improved, your healthcare provider may choose to stop the Zyprexa or keep you on Zyprexa at doses of Zyprexa 5 mg to 20 mg per day. The maximum dose for Zyprexa is 20 mg per day.
 
(Zyprexa Dosage Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;