Zyprexa Dosage

The recommended starting dosage for schizophrenia is Zyprexa 5 mg to 10 mg once daily. For the treatment of bipolar disorder, the recommended starting dose is 10 mg to 15 mg once daily. With either condition, the maximum dose of Zyprexa is 20 mg a day. Your age and other medical conditions you may have are among the factors that can affect the amount you are prescribed.

An Introduction to Zyprexa Dosing

The dose of Zyprexa® (olanzapine) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • The medical condition being treated
  • Your age
  • The severity of your condition
  • Other medical conditions you may have
  • Other medications you may be currently taking.
     
As always, do not adjust this amount unless your healthcare provider specifically tells you to do so.
 

Dosage of Zyprexa for Schizophrenia

The recommended starting Zyprexa dose for schizophrenia is 5 mg to 10 mg once daily. If you start at less than Zyprexa 10 mg daily, your healthcare provider may increase the dosage to 10 mg within the first few days.
 
After that, your healthcare provider may choose to increase the dosage further if symptoms continue, or decrease the dose if side effects occur. The maximum dose for Zyprexa is 20 mg per day.
 

Zyprexa Doses for Bipolar Mania or Mixed Episodes

The recommended starting Zyprexa dosage for treating manic or mixed episodes in bipolar disorder is Zyprexa 10 mg to 15 mg once daily. If bipolar disorder symptoms continue after several weeks, your healthcare provider may increase this amount.
 
If Zyprexa is used in combination with lithium (Eskalith®, Lithobid®) or valproate products (Depakene®, Depakote®, Depakote ER®), the recommended starting dose is generally Zyprexa 10 mg once daily.
 
Once your bipolar symptoms are improved, your healthcare provider may choose to stop Zyprexa or keep you on a dose ranging from 5 mg to 20 mg per day. The maximum Zyprexa dosage is 20 mg per day.
 
(Zyprexa Dosage Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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