Schizophrenia Channel
Topics
Medications
Quicklinks
Related Channels
Zyprexa Substitute
Zyprexa® (olanzapine) is a prescription medication used for treating bipolar disorder and schizophrenia. Although Zyprexa can be effective at treating these conditions, for some people it does not work or may cause side effects. Fortunately, there are several substitutes for Zyprexa. Some of these substitutes include therapy and other medications.
While it is unlikely that therapy alone can replace the need for medication in people who have bipolar disorder or schizophrenia, therapy can be an important part of a well-rounded treatment plan. Studies have shown that therapy can lead to increased mood stability, fewer hospitalizations, and improved functioning in several areas.
Also, there are many medications available for treating bipolar disorder or schizophrenia. These medications can include:
- Other atypical antipsychotics
- Older, typical antipsychotics
- Mood stabilizers (for bipolar disorder).
If Zyprexa is not working for you or if it is causing bothersome side effects, ask your healthcare provider about trying a Zyprexa substitute.
(Click Zyprexa Alternatives for a more in-depth look at potential substitutes for Zyprexa, such as therapy and other medications. This article also explains when it may be time to consider a substitute for Zyprexa.)

Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD